Webinar Review: Efficient Development for Separation Methods for Complex Natural Product Samples

Over the course of the semester, our trainees are reviewing webinars in their given fields and preparing abstracts to help colleagues outside their discipline make an informed choice about watching them. As our program bridges diverse disciplines, these abstracts are beneficial for our own group in helping one another gain key knowledge in each other’s fields. We are happy to share these here for anyone else who may find them helpful.

Efficient Development for Separation Methods for Complex Natural Product Samples

Dr. Tom Wheat, Principal Scientist (Waters Corporation)

Waters Corporation

Watch on the Waters Website >>

Shannon BernecheAnalysis by Shannon Berneche: 

This webinar is essential for understanding the basics of liquid chromatographic separation, an analytical technique which has become very useful in biomedical research and is also very often coupled to mass spectrometry (MS) to answer important chemical and biological questions.

In the field of MS research, collaborations are very common, as combining this powerful analytical technique with experiments involving cells or animals can often help in answering interesting biological questions. For this reason, I think it’s very useful for researchers in a variety of fields to understand the basics of what is an essential part of the most common MS workflows: liquid chromatography (LC).

This webinar explains why and how LC provides separation which aids in detection and characterization of chemicals (which is often by mass spectrometry). It explains the fundamentals of LC including how to get a good separation, determine whether your separation by LC was of good quality, and detection methods which are coupled to LC in order to access this chemical information in various ways.

It is always useful to learn about new techniques, and I think this webinar really gives a good introduction to the analytical technique of LC for those who are unfamiliar with it and would like to know why it is so useful and so commonly used in biochemical research, including often being coupled to MS for characterization of molecules.